On February 22-24, an event of symbolic significance for the Western Hemisphere took place in Latin America and could accelerate the movement towards a multipolar world order. Argentine President Alberto Fernandez visited Mexico at the invitation of its President Andres Manuel Lopez Obrador. The parties agreed on close cooperation in the fight against neoliberalism and for strengthening Latin American integration. Special attention was paid to the possibilities of the G20 as an experimental model of new (multilateral) international cooperation. An important point of the document signed by the two presidents was the issues of monitoring the elections in order to prevent attempts of a coup d'etat, as happened in Bolivia in October 2019. Then the pro-American opposition declared non-recognition of the election results and began to seize state buildings. Evo Morales was forced to leave the country. The meeting of Presidents Fernandez and Obrador was very positively reacted on the continent. There are renewed suggestions that an axis is being created that will accelerate the integration of the countries of the Caribbean, Central and South America. In Washington, however, the meeting of the presidents of two major Latin American states caused concern. Secretary of State Anthony Blinken held a teleconference with the heads of US diplomatic missions in Mexico and Canada; one of the topics of his conference was illegal migration from Central American countries to the United States through Mexico. Trump's project to build a wall on the border with Mexico is closed, and the flow of illegal immigrants coming to the United States through the southern border continues to worry the administration in Washington. The US pressure on Mexico continues under the pretext of fighting drug cartels. Last year, there was a major scandal between the United States and Mexico over an attempt to detain a Mexican general and former defense minister Salvador Cienfuegos. The Mexican authorities rejected accusations that their military was involved in ties with drug cartels, and a judge in the United States was forced to drop the charges. Many Mexican politicians have expressed concern about how deeply US agents are penetrating Mexican institutions. The results of this penetration have been noticeable in recent days. The US Drug Enforcement Agency has submitted more than 700 pages of conversations in support of the investigation and trial against Cienfuegos. At the end of February 2021, these documents were published, they consist of thousands of intercepted messages, photos, screenshots received between December 2015 and February 2017. US agents have engaged in such interceptions before, but only under Obrador were these operations regarded as gross interference in the internal affairs of the Mexican state. At the initiative of the President of Mexico, the Parliament adopted a new law aimed at limiting interaction with the United States. And in the United States, there is clearly an increased interest in the southern neighbor; for example, special resources dedicated to monitoring the situation with violence in Mexico have appeared. And if accusations of human rights violations are a standard pretext for US interference in the internal affairs of other countries, as in Libya and Syria, then at some point Mexico may be declared an outcast, against which the "democratic forces" will begin to "take measures". Currently, Mexico is defined in the United States as the main supplier of heroin, but for the United States, Mexico is the second largest export market and the third largest import market, which Washington has to take into account. And the political situation in Mexico looks unusual. The President is a representative of the socially oriented Movement of National Revival (MORENA) party. The castling of the two oldest political groups – the Institutional Revolutionary Party and the right-wing National Action Party-has ended. Even before being elected president in 2018, Obrador was quite critical of the United States, and opposition to plans to build a "Trump wall" on the border added to his popularity. Now the unusual political course of Mexico is also being understood in Argentina.